Rita Wilson, aka Ms. Tom Hanks, is looking to bring the novel Middlesex to the small screen as an hour-long drama on HBO. I'm not sure what to think about that. I can see how it would work - following the life of a hermaphrodite - but do you think people would watch it?
I tried to think of other books that have become TV shows: Little House on the Prairie, Friday Night Lights, Gossip Girl, True Blood (those last two are based on books, right?)... but what else? I think this is less of an occurrence than book-to-big-screen.